Promethazine with Codeine is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough.
Promethazine with Codeine contains an opioid (narcotic) cough medicine, and may be habit-forming.
Promethazine with Codeine may also be used for purposes not listed in this medication guide.
How should I take Promethazine with Codeine?
Follow the directions on your prescription label and read all medication guides. Never use this medicine in larger amounts, or for longer than prescribed. Take this medicine only until your symptoms clear up.
Never share opioid medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away opioid medicine is against the law.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Rinse after each use.
Call your doctor if your symptoms do not improve after 5 days of treatment.
If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken a cough or cold medicine within the past few days.
Store at room temperature away from moisture, heat, and light. Keep track of your medicine. You should be aware if anyone is using your medicine improperly or without a prescription.
Do not keep leftover medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Read and carefully follow the instructions provided with this medicine about how to safely dispose of any unused portion.
Before taking this medicine
You should not use Promethazine with Codeine if you are allergic to codeine or promethazine, or if you have:
- asthma or severe breathing problems;
- a stomach or bowel obstruction (including paralytic ileus);
- narrow-angle glaucoma; or
- if you are unable to urinate.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Promethazine with Codeine is not approved for use by anyone younger than 12 years old.
Do not give this medicine to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.
Tell your doctor if you have ever had:
- lung disease or breathing problems;
- a head injury, brain tumor, or seizure;
- constipation, a bowel obstruction, or stomach problems;
- problems with your bile duct, pancreas, or adrenal gland;
- an enlarged prostate or urination problems;
- uncontrolled muscle spasms;
- a blood cell disorder;
- neuroleptic malignant syndrome (a severe nervous system reaction);
- liver or kidney disease;
- low blood pressure;
- a drug addiction; or
- if you have a fever and cough with mucus.
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